Background: Patients with Lyme disease often suffer from neuro-motor sequelae following Borrelia infection, leading to impairments in balance, posture, and spinal musculoskeletal functionality. This study aims to evaluate the effectiveness of physical therapy in addressing these impairments. Methods: Initial assessments were conducted using the GPS Posture-test System to evaluate static bipodal balance and posture, and BACKFIX Technology for unipedal balance and spinal functionality. Disturbances in balance, postural asymmetries, and a forward-shifted center of gravity were observed. The patient then underwent two 10 sessions (each during two weeks) of computer-assisted physical therapy focused on neuro-muscular movement and balance control. Results: Post-therapy evaluations showed significant improvements in both bipodal and unipedal static balance, segmental and overall body posture, and spinal musculoskeletal functionality. The therapy effectively addressed the postural asymmetries and shifted the center of gravity closer to the optimal vertical posture point. Conclusion: Computer-assisted physical therapy with visual feedback significantly improved posture, balance, and spinal functionality in patients with Lyme disease-related neuro-motor sequelae. This approach facilitated the restoration of muscle coordination and enhanced motor control, aligning with findings from the existing literature.
The scientific and medical world is making permanent efforts to study, understand, and cure the complicated pathology of Systemic Lupus Erythematosus (SLE) – the disease with 100 faces, due to the diversity and complexity of the symptoms. SLE has a devastating impact on the patient’s life, causing multiple metabolic imbalances produced by both the disease itself and the necessary medication. This case report addresses the therapeutic aspects of SLE and diabetes mellitus, on a 47-year-old male with a sensitive multi-pathology and aggressive evolution, medication, and approaching psychomotor rehabilitation therapy, up to now, when SLE treatment has ended. Also, this case study report highlights the importance of flexibility in the psychomotor rehabilitation strategy, in the context of a large range of factors that influence its definition.
Objective: The study subject approaches a topic of cerebral pathology, namely the development of a pathological diagnosis that is as accurate as possible for the cerebral tumors and the metastases, using a new method that complements the optical microscopic examination and immunohistochemistry to correctly diagnose cerebral malignancies. Methods: Two-photon excitation (TPE) microscopy techniques are non-linear optical imaging methods that are gaining momentum in the investigation of fixed tissue sections, fresh tissue, or even for in vivo experiments. This method can be used for offering complementary information on the tissue architecture. We argue that using non-linear optical microscopy (which includes TPE microscopy) images collected on this category of brain tissue samples, can facilitate the interpretation of brain tumors and metastases, thus it is a solution worthy to explore. Scanning large areas of the lesions is important to avoid false-negative diagnoses because lesions are often non-uniform. Finding potential invasion sites is also restricted when using a narrow field-of-view imaging method. Results: Our study demonstrated that TPE microscopy can detect specific cellular features of cerebral tumors and metastases in good correlation with histopathological results. This approach can improve the accuracy of the cerebral tumors diagnosis and possibly other neoplasms. Conclusion: TPE microscopy is very important for future research because it could prevent the false or inadequate diagnosis of specific lesions and differentiate a primary tumor from a metastasis. The significance of the findings is attributable to cross-disciplinary cooperation and the constant use of a working standard across all of the experiments in this study.
