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The Role of Inflammation in the Pathogenesis of Psoriasis

1 - Discipline of Internal Medicine, Carol Davila University Central Emergency Military Hospital, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy,

2 - Dermatology Clinic, Carol Davila University Central Emergency Military Hospital, Bucharest, Romania

3 - Discipline of Dermatology, Colentina Clinical Hospital & Carol Davila University Central Emergency Military Hospital, Faculty of Medicine, Carol Davila University of

Correspondence: Mihaela Georgescu, georgescucmihaela@gmail.com

DOI: https://doi.org/10.55453/rjmm.2023.126.3.2

Received: December 27, 2022

Accepted: February 12, 2023

Abstract:

Psoriasis is a chronic inflammatory skin condition with genetic determinism characterized by the presence of well- defined, erythematous plaques, covered by white, pearly, stratified scales, located on the extension areas, the skin of the scalp, intertriginous regions. The origin of psoriasis is multifactorial, involving hereditary and environmental pathogenic mechanisms. It is triggered by various risk factors involving a variety of processes, such as inflammation, antigen presentation, cell signaling, and transcriptional regulation.

Keywords:

The Role of Inflammation in the Pathogenesis of Psoriasis

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APA Style

Costache, R.S., Georgescu, M., Ghilencea, A., Feroiu, O., Tiplica, S.G., & Costache, D.O. (2025). The role of inflammation in the pathogenesis of psoriasis. Romanian Journal of Military Medicine, 126(3), 245-253. https://doi.org/10.55453/rjmm.2023.126.3.2

Vancouver Style

Costache RS, Georgescu M, Ghilencea A, Feroiu O, Tiplica SG, Costache DO. The Role of Inflammation in the Pathogenesis of Psoriasis. Rom J Mil Med. 2025;126(3):245-253. doi:10.55453/rjmm.2023.126.3.2.

Harvard Style

Costache, R.S., Georgescu, M., Ghilencea, A., Feroiu, O., Tiplica, S.G. & Costache, D.O. 2025, 'The Role of Inflammation in the Pathogenesis of Psoriasis', Romanian Journal of Military Medicine, vol. 126, no. 3, pp. 245-253, doi:10.55453/rjmm.2023.126.3.2.