The Role of Diffusion-weighted Magnetic Resonance as a Potential Biomarker in the Characterization of Ovarian Tumor Lesions and the Assessment of Post-treatment Evolution

Ioana A. Negoiță^{1, 2}, Alexandru C. Filip^1,*, Florin Năftănăilă-Mali^{1, 2}, Elena D. Soloman-Năftănăilă-Mali¹, Ioana M. Cobani¹, Anca P. Cucu^{1, 2}

1 - “Dr. Carol Davila” Central University Emergency Military Hospital, Bucharest, Romania; alexandru.filip95@yahoo.com(ACF), aleinegoita@gmail.com (IAN);
2 - “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

Correspondence: Alexandru C. Filip, alexandru.filip95@yahoo.com

DOI: https://doi.org/10.55453/rjmm.2024.127.4.3

Received: December 5, 2023

Accepted: January 7, 2024

Abstract:

This paper focuses on the role of diffusion-weighted MRI of ovarian tumors as a potential biomarker to detect and characterize malignancy, and to improve the accuracy of preoperative diagnosis and postoperative follow-up to optimize therapeutic management. This is an original retrospective study of 76 patients with ovarian masses who underwent surgery between May 2014 and March 2016 at the “Dr Carol Davila” Central Military University Gynaecology Department. Patients underwent preoperative, 6-month, and 12-month postoperative evaluation of ovarian tumors using diffusion-weighted MRI. Due to the accuracy of this method using specific sequences in tissue characterization, magnetic resonance imaging can be used in the diagnostic work-up of complex adnexal masses.

Keywords:

ADC, biomarkers, borderline ovarian tumor, MRI, ovarian tumor, postoperative follow-up