Atypical fibroxanthoma and hemosiderotic dermatofibroma are both dermal tumors that can raise significant challenges for differential diagnosis. The definitive diagnosis is established based on histopathological appearance and immunohistochemistry. The aim of this paper is to present the differential diagnosis challenges encountered in the case of a 67-year-old male patient who developed within a month, following trauma to the lower third of the right thigh, a large asymptomatic tumor with an irregular outline.
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