Author: Alexandru Michire

Correlation Between Rectal Cancer and AB0 Blood Groups – Myth or Reality?

AB0 blood group type has been linked with different types of cancer. For rectal cancer, there isn’t enough data to assess whether such risk exists. We conducted a retrospective study to evaluate the association between ABO blood type and risk of susceptibility to development, progression, or protection against rectal cancer. We analyzed the medical records of 690 patients with rectal cancer from “Prof. Dr. Alexandru Trestioreanu” Oncological Institute of Bucharest during 8 years of follow-up. Data were scraped using Python. For analysis, we used the Chi-square test. The blood group count was A (287, 41.6.%) followed by 0 (250, 36.2%), B (32, 4.6%), and AB (121, 17.5%). There are no differences in the female and male subgroups regarding blood type and the lack of evidence for the null hypothesis rejection was shown using the χ2 test statistic (χ2 = 2.1, d.f. 3, p = 0.55 for males and χ2 = 2.9, d.f. 3, p = 0.4 for females). These findings are consistent with the notion that even if AB0 blood type is a risk factor for many types of cancer, there is no specific association between rectal cancer and blood group type.