Retinal migraine, a contentious clinical entity

1 - Department of Neurology, ‘Dr. Carol Davila’ Central Military Emergency University Hospital, 134 Calea Plevnei, 010242, Bucharest, Romania

2 - Department of Internal medicine and Gastroenterology, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Str, 050474, Bucharest, Romania

3 - Department No. 5, University of Medicine and Pharmacy “Carol Davila”, 050474 Bucharest, Romania

4 - Clinical Neurosciences Department, University of Medicine and Pharmacy "Carol Davila" Bucharest, 050474, Romania

5 - Department No. 1, University of Medicine and Pharmacy “Carol Davila”, 050474 Bucharest, Romania

6 - Department of Medico Surgical and Prophylactic Disciplines, Faculty of Medicine, ‘Titu Maiorescu’ University, 031593 Bucharest, Romania 571

Correspondence: Raluca S. Costache, Constantin Stefani

DOI: https://doi.org/10.55453/rjmm.2022.125.4.5

Received: July 04, 2022

Accepted: September 28, 2022

Abstract:

Retinal migraine (ophthalmic migraine, ocular migraine, anterior visual pathway migraine) is a rarely encountered medical condition, but with an interesting and complex clinical presentation. The goal of this article is to compile the literature on retinal migraine, detailing nomenclature, pathophysiology, differential diagnosis, and medical investigations including newer imaging modalities, like optical coherence tomography (OCT). We will approach topics of great concern such as risk factors, complications, treatment, and management of this condition. Retinal migraine is mainly a diagnosis of exclusion and it must be isolated from transient monocular vision loss (TMVL) developed from other causes, for instance, papilledema, giant cell arteritis, carotid artery disease (amaurosis fugax), intermittent angle closure glaucoma, and others. Its treatment is similar to migraine treatment; topiramate, amitriptyline, and nortriptyline are some of the pharmacological drugs successfully used.

Keywords:

Retinal migraine, a contentious clinical entity

Cite this article

APA Style

Sîrbu, C.A., Nicolescu, V.M., Nițiș, A.O., Costache, R.S., Ștefani, C., Mitrica, M., Luncă, D.C., & Anghel, D. (2025). Retinal migraine, a contentious clinical entity. Romanian Journal of Military Medicine, 125(4), 571-576. https://doi.org/10.55453/rjmm.2022.125.4.5

Vancouver Style

Sîrbu CA, Nicolescu VM, Nițiș AO, Costache RS, Ștefani C, Mitrica M, et al. Retinal migraine, a contentious clinical entity. Rom J Mil Med. 2025;125(4):571-576. doi:10.55453/rjmm.2022.125.4.5.

Harvard Style

Sîrbu, C.A., Nicolescu, V.M., Nițiș, A.O., Costache, R.S., Ștefani, C., Mitrica, M., Luncă, D.C. & Anghel, D. 2025, 'Retinal migraine, a contentious clinical entity', Romanian Journal of Military Medicine, vol. 125, no. 4, pp. 571-576, doi:10.55453/rjmm.2022.125.4.5.