The rise of antimicrobial resistance poses a significant challenge to global health. This study investigates the antimicrobial properties of Taraxacum officinale and Chelidonium majus. Taraxacum officinale, commonly known as dandelion, has been utilized for centuries in traditional medicine for its various therapeutic benefits, including treating cholecystitis, enhancing hepatic function, regulating blood pressure and cholesterol levels, and exhibiting diuretic effects. Additionally, research has indicated that infusions derived from this plant offer favorable outcomes in managing renal diseases. This study aims to assess the antimicrobial activity of extracts from Taraxacum officinale and Chelidonium majus employing qualitative screening, quantitative determination, and in vitro evaluation of anti-biofilm properties. In vitro evaluation of the antibiofilm activity of plant products revealed their ability to inhibit the development of biofilms on inert substrate; plant extracts of C. majus were found to inhibit biofilm formation in all bacterial strains tested, while tincture of T. officinale showed very good activity on gram-negative and fungal strains. The results obtained are promising, supporting further research into the biochemical characteristics of these extracts in order to formulate strategies for the control of bacterial and fungal infections in humans.
