Background: Occupational cancer is one of the most common occupational diseases. Identifying exposure to carcinogens is important both for implementing measures to prevent and control the risk of exposure and for the post-exposure medical surveillance of workers. The purpose of this study is to develop and validate a questionnaire that can be used in clinical practice to identify exposure and ultimately facilitate the diagnosis of occupational cancer. Methods: The first step involves designing the questionnaire, which will then be validated in the second step by ensuring it meets all the validation criteria for a questionnaire. Results: Scientific validation, logical validation, and construct validation were completed to ensure that the questionnaire is appropriate both structurally and in terms of content. The questionnaire was evaluated by comparing it to a reference standard, and the results, based on the exposure risk level category, showed good agreement (k = 0.719). The intra-observer and inter-observer reliability tests showed an excellent concordance for exposure risk level category (k = 1.000 and k = 0.945). Conclusions: The questionnaire was developed and validated to identify the risk of occupational cancer, and its systematic use in Romania could make a better selection of subjects who should be included in the post-exposure surveillance.
This study analyzes the satisfaction of the patients with radical prostatectomy according to the signs and symptoms included in the EORTC QLQ – C30 and EORTC QLQ – PR25 questionnaires, including their relation with the health state that influences the pre and postoperative life quality. Fifty patients with prostate cancer in a localized stage were studied and analyzed in a prospective manner and for a period of 12 months, before and 6 months after the radical prostatectomy. In choosing the patients, the common denominator was the use of the same postoperative plan and the lack of postoperative complications, as well as the lack of chronic diseases. Erectile dysfunction, urine incontinence were quite frequent after radical prostatectomy, while the urinary obstruction and the weak urinary stream were less frequent. In this regard, people noticed a significant decrease of life quality. Although the study addressed a small group of patients, the results are similar to those belonging to other clinical studies. Even if the aspect of life quality is more rarely taken into account, the questionnaires regarding the life quality are specific, useful and quite cheap in evaluating different therapies.
