Several studies have shown that some countries are among the main users of structural, molecular and physiologic information of human, animal, plant, and microorganisms cells (genetic and biological reserves) against living of organisms, especially humans. This method used as a mechanism for removing their rivals and opponents to achieve their goals. This descriptive-analytical study was designed to define the concept of bioterrorism, passive defense, and genetic resources and its historical development process, with emphasis on efforts to control these types of threats over time. In the present review, a wide range of literature through the search on Google Scholar, PubMed, Medline, and Scopus databases, extracted without regard to time constraints and focusing on the keywords listed above with three valid criteria and new sources of resources. The explanation of the material was based on the data obtained from the review of the sources and based on the inferences of the researchers from them. Given the importance of genetic information and the lack of clear prospective research in this area, the confidentiality of genetic data has been particularly respected among researchers. Eliminating data security can lead to unplanned advertising and costs. Therefore, the existence of laws and protective measures against coping with the misuse of enemies from genetic information is more than other country's prior demand.