Background: Although CBCT was introduced in dentistry, it has a specific role in rhinology for assessing uncomplicated maxillary sinusitis. CBCT offers valuable information on anatomy and pathology with a low irradiation dose. Methods: We performed a systematic search on PubMed on the use of CBCT in detecting maxillary sinus pathology and the relation between dental lesions and maxillary sinusitis. Results: Specific findings, such as mucosal thickening, retention cysts, or antroliths, have been found to be associated with dental problems. These alterations can be incidental findings during the management plan for patients with dental problems, but can also be the reason that prompts the patient to perform the imaging investigation. Conclusions: The literature on the topic is quite comprehensive and clarifies percentages and the correct use of CBCT. As a minimally invasive procedure, CBCT finds its utility in assessing patients with dental problems, as they are more prone to accepting this fast, pain-free, and non- claustrophobic method. There are several limitations, such as the not-so-large target area and the less-than-average, limited pictures. However, CBCT remains a valuable tool that can be used for patients with suspected sinus problems that require dental treatment to ensure there are no future sinus complications.