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A brief overview of the Epstein Barr virus and its association with Burkitt’s lymphoma

Mahdieh Farzanehpour1, Amir M.M. Fard1, Hadi E.G. Ghaleh1,* ✉

1 - Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

Correspondence: Hadi Esmaeili Gouvarchin Ghaleh

DOI: https://doi.org/10.55453/rjmm.2022.125.3.4

Received: December 07, 2021

Accepted: March 18, 2022

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Abstract:

Epstein Barr virus (EBV) is known as an oncovirus and associates with several human malignancies such as Burkitt’s lymphoma, other non-Hodgkin lymphomas, nasopharyngeal carcinoma, Hodgkin’s disease, gastric adenocarcinoma, etc. in Burkitt’s lymphoma, and the key event is the translocation of MYC gene, that increase of cell survival and aberrant expression of MYC gene. The biology of EBV and its function in the development of Burkitt’s lymphoma are discussed in this review.

Keywords:
Burkitt's lymphoma, Epstein Barr virus, MYC gene, oncovirus

A brief overview of the Epstein Barr virus and its association with Burkitt’s lymphoma

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APA Style

Farzanehpour, M., Fard, A.M., & Ghaleh, H.E. (2025). A brief overview of the epstein barr virus and its association with burkitt’s lymphoma. Romanian Journal of Military Medicine, 125(3), 373-381. https://doi.org/10.55453/rjmm.2022.125.3.4

Vancouver Style

Farzanehpour M, Fard AM, Ghaleh HE. A brief overview of the Epstein Barr virus and its association with Burkitt’s lymphoma. Rom J Mil Med. 2025;125(3):373-381. doi:10.55453/rjmm.2022.125.3.4.

Harvard Style

Farzanehpour, M., Fard, A.M. & Ghaleh, H.E. 2025, 'A brief overview of the Epstein Barr virus and its association with Burkitt’s lymphoma', Romanian Journal of Military Medicine, vol. 125, no. 3, pp. 373-381, doi:10.55453/rjmm.2022.125.3.4.