Author: A. Aungurenci

Antibiotic resistant urinary tract infections in an urology ward

Introduction: UTI (urinary tract infections) represent a central pathology for a urological service. Antibiotic resistance is growing at a steady and alarming rate worldwide and especially in Romania. Method and materials: We have analyzed all the patients that were admitted to our clinic for continuous hospitalization between January 2015 and October 2015. All patients undergone urine culture and all cultures positive had an antibiogram worked up. We have selected all patients that had antibiotic resistance to at least an antibiotic. Results: From 1745 patients admitted for continuous hospitalization, we had 180 positive urine cultures at admission from which 125 had at least an antibiotic resistance. Conclusions: Antibiotic resistance is a serious phenomenon, with potential lethal complications, which we encounter daily in urological practice INTRODUCTION Uncomplicated UTI are probably the most common urological condition. It is estimated that at least 1 out of 3 females will develop an UTI during their lifetime. UTI frequency at young females is associated with sexual intercourse. When urological malformations, pregnancy, menopause, urolithiasis occur conditions for recurrence of the disease are met. Recurrences are defined as at least 2 episodes of UTI in 6 months or 3 episodes a year. Male patients develop UTI due to different mechanisms and at an elderly age. The most common mechanism that facilitates the development of UTI in men is bladder outlet obstruction caused mainly by prostatic enlargement. UTI are caused mainly by Gram negative enterobacteriacea. Escherichia Coli is the cause for about 80-90 % of community acquired UTI’s. In healthcare related infections E. Coli is still the leading cause but with a more modest percentage. Other pathogens that cause UTI are: Proteus mirabilis, Enterococous, Klebsiella pneumonie, Pseudomonas aeruginosa. METHOD AND MATERIALS Between January and October 2015, 1745 patients were admitted for continuous hospitalization in our Clinic. At admission all of these patients had their urine sent for culture. The urine culture was tested for antibiotic response for the following antibiotics: 1 Carol Davila Central Emergency Military Hospital, Bucharest 2 Carol Davila University of Medicine and Pharmacy, Faculty of Medicine, Bucharest 20