Complications of systemic lupus erythematosus: A review

1 - University of Medicine

2 - University of Medicine

3 - St. Pantelimon Hospital, Department of General Surgery, Bucharest, Romania

4 - Urology Department, Central University Emergency Military Hospital, Bucharest, Romania

5 - Gastroenterology Department, Central University Emergency Military Hospital, Bucharest, Romania

6 - Clinical Emergency Hospital of Bucharest, Bucharest, Romania

Correspondence: Camelia Diaconu PhD

Received: September 30, 2018

Accepted: November 1, 2018

Abstract:

Systemic lupus erythematosus (SLE) is a complex autoimmune condition, which often evolves with severe complications. In SLE, autoantibodies appear, with systemic inflammation and multiple tissue destructions. SLE is the most common form of lupus and is considered more severe than other forms. SLE can affect many parts of the body, including the kidneys, heart, lungs, brain, blood, and skin. Symptoms vary among patients. SLE can follow an unpredictable pattern of remissions (symptoms improve) and flares (symptoms worsen). Renal involvement is one of the most severe complications in SLE patients. The process of depositing the immune complexes in the kidneys could lead to the appearance of lupus nephritis. If the treatment is early and treat-to-target, it can change the course of the renal disease.

Keywords:

Complications of systemic lupus erythematosus: A review

Cite this article

APA Style

Iftimie, G., Stoian, A.P., Socea, B., Motofei, I., Marcu, D., Costache, R.S., & Diaconu, C. (2025). Complications of systemic lupus erythematosus: a review. Romanian Journal of Military Medicine, 121(3), 9-15.

Vancouver Style

Iftimie G, Stoian AP, Socea B, Motofei I, Marcu D, Costache RS, et al. Complications of systemic lupus erythematosus: A review. Rom J Mil Med. 2025;121(3):9-15.

Harvard Style

Iftimie, G., Stoian, A.P., Socea, B., Motofei, I., Marcu, D., Costache, R.S. & Diaconu, C. 2025, 'Complications of systemic lupus erythematosus: A review', Romanian Journal of Military Medicine, vol. 121, no. 3, pp. 9-15.