Rare case of Stevens-Johnson-TEN overlap syndrome caused by mycotoxins

Cristian Cobilinschi^{1,* ✉}, Radu C. Tincu^{2, 3}, Mihail S. Tudosie³, Zoie Ghiorghiu², Radu A. Macovei^{2, 3}

1 - Anesthesiology and Intensive Care Unit Department, Clinical Emergency Hospital, Bucharest
2 - Anesthesiology and Intensive Care – Toxicology Unit Department, Clinical Emergency Hospital, Bucharest
3 - Carol Davila University of Medicine and Pharmacy, Bucharest

Correspondence: Cristian Cobilinschi, MD

Received: February 15, 2018

Accepted: May 21, 2018

Abstract:

Mushroom poisoning is rarely associated with skin involvement. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening mucocutaneous reactions, characterized by extensive necrosis. SJS/TEN overlap includes patients with skin exfoliation between 10 to 30 percent of the body surface area. We report the case of a patient that was assumed to have ingested one type of toxic mushroom within the twelve hours prior to the appearance of skin lesions typical for SJS/TEN overlap syndrome.